Work

The work will be dedicated to the development of new types of azolo- and azino-annulated trifluoromethylpyrimidines, analogues of pyrrolo (pyrido) [1,2-α] quinazoline alkaloids, thiazolo (triazolo-, pyrazolo) and diazino azines that are focused on the issues of modern medicinal chemistry. Design and transformation of condensed derivatives, containing prospective for structural modification haloalkyl, formyl, carboxyl, alkenyl, alkynyl, hydrazino and amino groups will be principally considered. An improving of already known relevant methods of functionalization and annulation of small and medium heterocyclic nuclei to azine and azepine templates and a developing of new conforming methods for modern organic chemistry are planned for achieving the goal.