Work

Cycle of scientific works contains summarized results of basic and applied researches of the role of probiotics, created on the base of various groups of non-pathogenic microorganisms, prebiotic supplements and immunoregulatory cytokines, to the formation of body immunoresistance and dysbiotic states correction in cases of physiological norm and pathological conditions. A comprehensive study of the lactulose and lactitol effect on the biological properties of bacilli probiotic strains and based on them synbiotic drug "Bacilakt®" carried out for the first time and its effectiveness on the experimental dysbiosis was proved. New science-based approaches for macroorganism immunoresistance increasing by lacto- and bifidobacteria which regulate immune response by balancing production of cytokines, especially Th1-type – interferon- (ІFN-) and interleukin-2 (ІL-2) were developed.